Significant Allergic Reactions. Promethazine/phenylephrine/codeine may possibly induce allergic reactions, which may be major. Cease using promethazine/phenylephrine/codeine and get assistance right away Should you have any of the next signs and symptoms of a significant allergic response.
Having said that, codeine should be administered only beneath shut supervision to patients having a background of drug abuse or dependence
Opvee® (nalmefene) is really a nasal spray utilized for the unexpected emergency cure of the acknowledged or suspected opioid overdose in Grown ups and children ages 12 many years and more mature. This is simply not a substitute for unexpected emergency clinical treatment.
Discuss with your wellbeing care service provider or simply a pharmacist to learn if a medicine your son or daughter is getting incorporates codeine or tramadol.
Notify your physician For those who have ever had any unusual or allergic response to this medicine or another medicines. Also convey to your overall health care Experienced In case you have any other types of allergy symptoms, which include to foods, dyes, preservatives, or animals. For non-prescription products and solutions, examine the label or deal substances carefully.
Children using this genetic variation who were prescribed codeine just after tonsillectomy and/or adenoidectomy for obstructive rest apnea could be at best hazard according to studies of quite a few deaths in this population as a consequence of respiratory melancholy. As a result, codeine is contraindicated in all little ones who undertake tonsillectomy and/or adenoidectomy. Suggest caregivers of children obtaining codeine for other factors to watch for signs of respiratory depression.
Concomitantadministration of promethazine products and solutions with other respiratory depressantshas an Affiliation with respiratory melancholy, and in some cases Loss of life, inpediatric clients.
Bone Marrow Suppression. Promethazine/phenylephrine/codeine could lead to your bone marrow not to make sufficient cells. This may result in minimal blood levels of critical cells, for instance pink blood cells, white blood cells, platelets, and neutrophils.
The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric patients less than six years of age, for the reason that The mixture may lead to deadly respiratory despair On this age population. It is crucial that Promethazine Hydrochloride and Codeine Phosphate Syrup is calculated using an precise measuring product (see PRECAUTIONS- Facts for Clients).
Promethazine must be utilised cautiously in persons with cardiovascular disease or with impairment of liver function.
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Bone marrow suppression can lead to infections or bleeding. This can be really serious or simply lifestyle-threatening. Preserve more info all appointments to acquire your blood checked. Convey to your healthcare provider at once In case you have any of the subsequent signs of bone marrow suppression.